Featured Publications

Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
 Arias-Palomo E, Puri N, O’Shea Murray VL, Yan Q, Berger JM.  Mol Cell. 2019 Apr 4;74(1):173-184.

Topoisomerase VI senses and exploits both DNA crossings and bends to facilitate strand passage.
Wendorff TJ and Berger JM.  Elife. 2018, Mar 29;7.

Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor.
Thomsen ND, Lawson MR, Witkowsky LB, Qu S, Berger JM. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7691-E7700.

Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein.
Lawson MR, Ma W, Bellecourt MJ, Artsimovitch I, Martin A, Landick R, Schulten K, Berger JM.  Mol Cell. 2018. Sep 20;71(6):911-922.

Mechanisms for initiating cellular DNA replication.
Bleichert F, Botchan MR, Berger JM.  Science. 2017 Feb 24;355(6327).

Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis.
Blower TR, Williamson BH, Kerns RJ, Berger JMProc Natl Acad Sci U S A. 2016 Feb 16;113(7):1706-13

Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.
Bleichert F, Leitner A, Aebersold R, Botchan MR, Berger JM. Proc Natl Acad Sci U S A. 2018;115( 6):E5906-E5915.

Ligand-induced and small-molecule control of substrate loading in a hexameric helicase.
Lawson MR, Dyer K, Berger JM.  Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):13714-13719.

Viral hijacking of a replicative helicase loader and its implications for helicase loading control and phage replication.
Hood IV, Berger JMElife. 2016 May 31;5. pii: e14158. doi: 10.7554/eLife.14158.

A complete list of publications, excluding chapters and articles not accessed by PubMed, can be found at http://www.ncbi.nlm.nih.gov/sites/myncbi/james.berger.1/bibliograpahy/40436728/public/?sort=date&direction=ascending