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Post-doc positions available


Featured Publications

Lee JH, Mosher EP, Lee YS, Bumpus NN, Berger JM. Control of topoisomerase II activity and chemotherapeutic inhibition by TCA cycle metabolites. Cell Chem Biol. 2021 Sep 11:S2451-9456(21)00403-7.


Puri N, Fernandez AJ, O’Shea Murray VL, McMillan S, Keck JL, Berger JM. The molecular coupling between substrate recognition and ATP turnover in a AAA+ hexameric helicase loader. Elife. 2021 May 26;10:e64232


Attali I, Botchan MR, Berger JM. Structural Mechanisms for Replicating DNA in Eukaryotes. Annu Rev Biochem. 2021 Jun 20;90:77-106.

Modulated control of DNA supercoiling balance by the DNA-wrapping domain of bacterial gyrase.
Hobson MJ, Bryant Z, Berger JM.  Nucleic Acids Res. 2020 Feb 28;48(4):2035-2049.


Physical Basis for the Loading of a Bacterial Replicative Helicase onto DNA.
 Arias-Palomo E, Puri N, O’Shea Murray VL, Yan Q, Berger JM.  Mol Cell. 2019 Apr 4;74(1):173-184.


A new class of disordered elements controls DNA replication through initiator self-assembly.
Parker MW, Bell M, Mir M, Kao JA, Darzacq X, Botchan MR, Berger JM.  Elife. 2019 Sep 27;8. pii: e48562.

Mechanism for the Regulated Control of Bacterial Transcription Termination by a Universal Adaptor Protein.
Lawson MR, Ma W, Bellecourt MJ, Artsimovitch I, Martin A, Landick R, Schulten K, Berger JM.  Mol Cell. 2018. Sep 20;71(6):911-922.


Conformational control and DNA-binding mechanism of the metazoan origin recognition complex.
Bleichert F, Leitner A, Aebersold R, Botchan MR, Berger JM. Proc Natl Acad Sci U S A. 2018;115( 6):E5906-E5915.

A complete list of publications, excluding chapters and articles not accessed by PubMed, can be found at http://www.ncbi.nlm.nih.gov/sites/myncbi/james.berger.1/bibliograpahy/40436728/public/?sort=date&direction=ascending